Little Italy Towers in San Diego, California by RD Riccoboni. Urban chic lifestyle and high rise loft dwellings abound in the new Little Italy as the old slowly disappears into abstract realism as the new moves in and upward retaining the old world colors. Little Italy is Downtown San Diego's oldest continuous neighborhood business district. At one time, more than 6,000 Italian families lived in Little Italy and toiled to build San Diego into the center of the world tuna industry. Home to many business's and persons it also host many of the city fun festivals. Little is a blank canvas for some of San Diego's best and brightest artists and architects.